1. Introduction The relationship between industrial agriculture and human neurological health has become one of the most contentious and critical frontiers in modern environmental science. For the better part of a century, the global imperative to maximize crop yields has driven the widespread deployment of synthetic chemical agents designed to eradicate pests. Among these, the organophosphate class of insecticides has held a dominant position, with chlorpyrifos standing as a

1. Introduction 1.1 The Emergence of a Modern Plague The narrative of the Highly Pathogenic Avian Influenza (HPAI) A(H5N1) virus in the early 21st century is one of relentless adaptation and ecological expansion. While the virus has been a known entity in virology since its initial identification in Southern China in 1996, the lineage that confronts the United States in January 2026—clade 2.3.4.4b—represents a fundamentally distinct biological agent in terms of its host range