*note, this article is for research purposes only and does not constitute medical advice of any kind. The Emergence of a Novel Biological Threat The intersection of climatological shifts, vector ecology, and human immunology has precipitated a public health crisis in the United States that is only now beginning to be fully quantified. For over a decade, Alpha-gal Syndrome (AGS)—an IgE-mediated hypersensitivity to the oligosaccharide galactose-alpha-1,3-galactose—was regarded